To Evaluate the clinical characteristics of childhood-onset systemic lupus erythemoatosus (SLE) and analyse the factors related to outcome of renal function in lupus nephritis, we reviewed medical records of 18 cases of SLF diagnosed at the
Department
of Pediatrics. Pusan National University Hospital from January 1981 to December 1990.
@ES The results were as follow:
@EN 1)Male to female ratio was 1:2.6.
2) Nephropathy was the most common initial impression, and 8 cases were diagnosed as SLE at first.
3) The clinical menifestation. was ANA (+), malar rash, renal disorder, hematologic disorder in frequency.
4) Diffuse proliferative lupus nephritis was the most common in renal histopathologic studies.
5) Among the follow-up cases, active lupus was 39%, remission was 28%.
6) As factors related to outcome of lupus nephrits were, hypertension and proteinuria were siginificant statistically.
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